CBD snuff - McChrystal's Green & Original

volunge

McChrystal's just launched their O&G complimented with 20 mg of CBD per 8.75 g tin - GREEN & ORIGINAL.

Available only in Switzerland and Germany for the meantime.

https://www.snuffstore.de/schnupftabak/marken/mcchrystal-s/mcchrystal-s-green-and-original

https://twitter.com/mcchrystalsuk

StillLearning

I want

KebAMP

How efficiently CBD can be absorbed by the nose? That is the question...

Usually oils do not penetrate very well any type of skin or mucous.

mrmanos

You know, I've grown cannabis for a long time. I live in Colorado where it's legal. I make salves, tinctures, infused oil, etc. I can't possibly imagine taking cbd in the nose and getting any effect at all. I think it's just a shot at the burgeoning market. In my town we have cbd cat anxiety drops, you can even get it at Walmart. I love McChrystals O and G, we have it locally. In fact it's the only nasal snuff here! But cbd is over the top in my opinion.

rostanf

I wonder if lecithin would increase or enable absorption.

volunge

Having no experience with pure CBD oil, I was wondering what 20 mg actually means and ran a quick search. The usual CBD oil dosage in various indications ranges from 1 to 20 mg 1-2 times a day. There's a 2.28 mg of oil in 1 g of G&O, and such amount is capable of producing therapeutical effect. https://bluecloud.org/cbd-oil-dosage-explained/

@KebampIt Regarding absorption efficiency, oral mucosal absorption of CBD (tinctures) is a thing - sublingual administration is considered to be one of the most effective methods. Moreover, it is possible to convert CBD into water soluble form (mist) for nasal absorption http://www.nasadol.com/.

@mrmanos Sure, CBD is trendy nowadays. The first batch of G&O sold out flash-fast at snuffstore.de.

mrmanos

@rastanf Lecithin only works in your stomach, not the nose.

mrmanos

CBD has no effect on your senses, like thc does. I can't really think of any possible reason to add it to snuff other than the fact that it's very popular. I've made tinctures from pot I grew with a high level of cbd but never could detect anything mentally. If rubbed into the skin, yeah it helped soreness but no other effects.

rostanf

@mrmanos I'm not entirely sure about lecithin absorption nasally but it is is used as a mucoadhesive in some nasal sprays. It is a surfactant and a phospholipid. Here's an exerpt from a medical journal and a link with info on a nasal preparation with lecithin.
"Surface active agents, or surfactants, are amphiphilic molecules possessing both lipophilic and hydrophilic residues. Surfactants have various applications in pulmonary drug administration, due to their high interfacial activity; one of which is as an absorption enhancer. Surfactants can enhance
absorption with more than one mechanism; these include perturbing the cell membrane by leaching of
membrane proteins, opening of tight junctions, or preventing enzymatic degradation of the drugs
These surfactants are mainly used and studied in oral drug administration; however, there have been
a few studies looking at their application in nasal and pulmonary drug delivery. Surfactants used
as absorption enhancers can be classified as; (A) phospholipids, (B) bile salts, (such as sodium
taurocholate etc.), (C) non-ionic surfactants, (D) salt of fatty acids, and (E) alkyl glycosides
(e.g., tetradecylmaltoside, N-lauryl-b-d-maltopyranoside etc.)" https://www.hindawi.com/journals/ja/2014/146280/

volunge

Just FIY: "[..]CBD-drug interactions may be problematic in some cases. CBD and other plant cannabinoids can potentially interact with many pharmaceuticals by inhibiting the activity of cytochrome P450,
a family of liver enzymes. This key enzyme group metabolizes most of
the drugs we consume, including more than 60 percent of marketed meds."

More here: https://www.projectcbd.org/science/cannabis-pharmacology/cbd-drug-interactions-role-cytochrome-p450

frandelrio

Sorry to revive the post, but I have to say that a can of O&G CBD arrived today and I've been testing it.

I am a regular cannabis and hash user, and recently had the opportunity to smoke very low THC cannabis, officially almost pure CBD cannabis, and noticed something. The effect is relaxing on the body, but also on the mind, it feels a bit cloudy.

Now, the O&G CBD manages to relax me, and not only that, it even manages to give me a slight dizziness. It's funny because I have a very high tolerance to the effects of cannabis, as well as nicotine, but this tobacco manages to make me feel for a moment in a way that I have not felt before. It is not a mental effect, that is, I am not referring at all to the typical effect of being high, but to a slight fatigue (or mental and physical relaxation)
I will continue testing and contrasting experiences.

Gormur

I've thought about trying this but don't know if it'd be seized before it got to me.  Has anybody in North America ever ordered and received CBD snuffs?

Kengivens

Yeah, I received mine sometime last year. No issues. Dallas, Ft Worth

Gormur

Ah okay, thanks a lot.  I'll have to check it out

Bryceton

I bought some from Toque. Havent tried McChrystals product but from what i understand it is not as strong. You shouldnt have any problems as Hemp derived CBD has been nationally legalized. Only thing it does for me is make me drowsy and relaxed in general. I typically took a few pinches at night before bed and definately got to sleep faster than usual. Localized effects are anti inflammatory so it helped a little with congestion also.